Publications

2023

Inside out Porphyridium cruentum: Beyond the Conventional Biorefinery Concept

2023 ACS Sustainable Chemistry and Engineering ; 11 ; 381 - 389 Liberti D., Imbimbo P., Giustino E., D’Elia L., Ferraro G., Casillo A., Illiano A., Pinto G., Di Meo M.C., Alvarez-Rivera G., Corsaro M.M., Amoresano A., Zarrelli A., Ibáñez E., Merlino A., Monti D.M.
DOI: 10.1021/acssuschemeng.2c05869

In Vitro Study of the Blood–Brain Barrier Transport of Natural Compounds Recovered from Agrifood By-Products and Microalgae

2023 International Journal of Molecular Sciences ; 24 ; 533 Sánchez-Martínez J.D., Garcia A.R., Alvarez-Rivera G., Valdés A., Brito M.A., Cifuentes A.
DOI: 10.3390/ijms24010533

Metabolomic Characterization of the Antiproliferative Activity of Bioactive Compounds from Fruit By-Products Against Colon Cancer Cells

2023 Methods in Molecular Biology ; 2571 ; 45 - 55 Alvarez-Rivera G., Valdés A., Cifuentes A.
DOI: 10.1007/978-1-0716-2699-3_5

2022

Assessment of cocoa powder changes during the alkalization process using untargeted metabolomics

2022 LWT ; 172 ; 114207 Greño M., Herrero M., Cifuentes A., Marina M.L., Castro-Puyana M.
DOI: 10.1016/j.lwt.2022.114207

Synergic effect of natural deep eutectic solvent and high-intensity ultrasound on obtaining a ready-to-use genipin extract: Crosslinking and anti-neurodegenerative properties

2022 Food Chemistry: X ; 16 ; 100489 Isabel Landim Neves M., Socas-Rodríguez B., Valdés A., Keven Silva E., Cifuentes A., Angela A. Meireles M., Ibáñez E.
DOI: 10.1016/j.fochx.2022.100489

Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium pinifolium Phil.

2022 Antioxidants ; 11 ; 2313 Barrientos R.E., Ibáñez E., Puerta A., Padrón J.M., Paredes A., Cifuentes F., Romero-Parra J., Palacios J., Bórquez J., Simirgiotis M.J.
DOI: 10.3390/antiox11122313

Metabolomics study of COVID-19 patients in four different clinical stages

2022 Scientific Reports ; 12 ; 1650 Valdés A., Moreno L.O., Rello S.R., Orduña A., Bernardo D., Cifuentes A.
DOI: 10.1038/s41598-022-05667-0

Nutritional Composition and Bioactive Compounds of Native Brazilian Fruits of the Arecaceae Family and Its Potential Applications for Health Promotion

2022 Revista de Ciencias Farmaceuticas Basica e Aplicada ; 14 ; 4009 Morais R.A., Teixeira G.L., Ferreira S.R.S., Cifuentes A., Block J.M.
DOI: 10.3390/nu14194009

Foodomics: Surfing the (analytical) wave

2022 Electrophoresis ; 43 ; 1813 Cifuentes A., Herrero M.
DOI: 10.1002/elps.202270114

Pressurized natural deep eutectic solvents: An alternative approach to agro-soy by-products

2022 Frontiers in Nutrition ; 9 ; 953169 Bragagnolo F.S., Socas-Rodríguez B., Mendiola J.A., Cifuentes A., Funari C.S., Ibáñez E.
DOI: 10.3389/fnut.2022.953169

Anti-inflammatory and neuroprotective evaluation of diverse microalgae extracts enriched in carotenoids

2022 Algal Research ; 67 ; 102830 Gallego R., Valdés A., Suárez-Montenegro Z.J., Sánchez-Martínez J.D., Cifuentes A., Ibáñez E., Herrero M.
DOI: 10.1016/j.algal.2022.102830

Pressurized green liquid extraction of betalains and phenolic compounds from Opuntia stricta var. Dillenii whole fruit: Process optimization and biological activities of green extracts

2022 Innovative Food Science and Emerging Technologies ; 80 ; 103066 Gómez-López I., Mendiola J.A., Portillo M.P., Cano M.P.
DOI: 10.1016/j.ifset.2022.103066

One-step sustainable extraction of Silymarin compounds of wild Algerian milk thistle (Silybum marianum) seeds using Gas Expanded Liquids

2022 Journal of Chromatography A ; 1675 ; 463147 Abderrezag N., Montenegro Z.J.S., Louaer O., Meniai A.-H., Cifuentes A., Ibáñez E., Mendiola J.A.
DOI: 10.1016/j.chroma.2022.463147

Flavonoid Accumulation Varies in Medicago truncatula in Response to Mercury Stress

2022 Frontiers in Plant Science ; 13 ; 933209 Alvarez-Rivera G., Sanz A., Cifuentes A., Ibánez E., Paape T., Lucas M.M., Pueyo J.J.
DOI: 10.3389/fpls.2022.933209

Study of the reaction between genipin and amino acids, dairy proteins, and milk to form a blue colorant ingredient

2022 Food Research International ; 157 ; 111240 Neves M.I.L., Valdés A., Silva E.K., Meireles M.A.A., Ibáñez E., Cifuentes A.
DOI: 10.1016/j.foodres.2022.111240

Study of the potential neuroprotective effect of Dunaliella salina extract in SH-SY5Y cell model

2022 Analytical and Bioanalytical Chemistry ; 414 ; 5357 - 5371 Gallego R., Valdés A., Sánchez-Martínez J.D., Suárez-Montenegro Z.J., Ibáñez E., Cifuentes A., Herrero M.
DOI: 10.1007/s00216-021-03819-1

Blood–Brain Barrier Permeability Study of Potential Neuroprotective Compounds Recovered From Plants and Agri-Food by-Products

2022 Frontiers in Nutrition ; 9 ; 924596 Sánchez-Martínez J.D., Valdés A., Gallego R., Suárez-Montenegro Z.J., Alarcón M., Ibañez E., Alvarez-Rivera G., Cifuentes A.
DOI: 10.3389/fnut.2022.924596

Metabolite Profiling of Soy By-Products: A Comprehensive Approach

2022 Journal of Agricultural and Food Chemistry ; 70 ; 7321 - 7341 Bragagnolo F.S., Álvarez-Rivera G., Breitkreitz M.C., Ibáñez E., Cifuentes A., Funari C.S.
DOI: 10.1021/acs.jafc.2c01050

Comparison of Four Oil Extraction Methods for Sinami Fruit (Oenocarpus mapora H. Karst): Evaluating Quality, Polyphenol Content and Antioxidant Activity

2022 Foods ; 11 ; 1518 Muñoz A.M., Casimiro-Gonzales S., Gómez-Coca R.B., Moreda W., Best I., Cajo-Pinche M.I., Loja J.F., Ibañez E., Cifuentes A., Ramos-Escudero F.
DOI: 10.3390/foods11101518

Safety assessment of citrus and olive by-products using a sustainable methodology based on natural deep eutectic solvents

2022 Journal of Chromatography A ; 1669 ; 462922 Socas-Rodríguez B., Mendiola J.A., Rodríguez-Delgado M.Á., Ibáñez E., Cifuentes A.
DOI: 10.1016/j.chroma.2022.462922

Characterization and incorporation of extracts from olive leaves obtained through maceration and supercritical extraction in Canola oil: Oxidative stability evaluation

2022 LWT ; 160 ; 113274 Dauber C., Carreras T., González L., Gámbaro A., Valdés A., Ibañez E., Vieitez I.
DOI: 10.1016/j.lwt.2022.113274

Metataxonomic and metabolomic evidence of biofilm homeostasis disruption related to caries: An in vitro study

2022 Molecular Oral Microbiology ; 37 ; 81 - 96 Sánchez M.C., Velapatiño A., Llama-Palacios A., Valdés A., Cifuentes A., Ciudad M.J., Collado L.
DOI: 10.1111/omi.12363

Neuroprotective potential of terpenoid-rich extracts from orange juice by-products obtained by pressurized liquid extraction

2022 Food Chemistry: X ; 13 ; 100242 Sánchez-Martínez J.D., Alvarez-Rivera G., Gallego R., Fagundes M.B., Valdés A., Mendiola J.A., Ibañez E., Cifuentes A.
DOI: 10.1016/j.fochx.2022.100242

Protein valorization from ora-pro-nobis leaves by compressed fluids biorefinery extractions

2022 Innovative Food Science and Emerging Technologies ; 76 ; 102926 Torres T.M.S., Mendiola J.A., Álvarez-Rivera G., Mazzutti S., Ibáñez E., Cifuentes A., Ferreira S.R.S.
DOI: 10.1016/j.ifset.2022.102926

Response surface methodology for the optimization of biophenols recovery from “alperujo” using supercritical fluid extraction. Comparison between Arbequina and Coratina cultivars

2022 Journal of Supercritical Fluids ; 180 ; 105460 Dauber C., Carreras T., Fernández Fernández A., Irigaray B., Albores S., Gámbaro A., Ibáñez E., Vieitez I.
DOI: 10.1016/j.supflu.2021.105460

Foodomics: Analytical Opportunities and Challenges

2022 Analytical Chemistry ; 94 ; 366 - 381 Valdés A., Álvarez-Rivera G., Socas-Rodríguez B., Herrero M., Ibáñez E., Cifuentes A.
DOI: 10.1021/acs.analchem.1c04678

Capillary electromigration methods for food analysis and Foodomics: Advances and applications in the period February 2019–February 2021

2022 Electrophoresis ; 43 ; 37 - 56 Valdés A., Álvarez-Rivera G., Socas-Rodríguez B., Herrero M., Cifuentes A.
DOI: 10.1002/elps.202100201

2021

Green microsaponification-based method for gas chromatography determination of sterol and squalene in cyanobacterial biomass

2021 Talanta; vol: 224 ; Páginas: 44 - 52 Fagundes, M.B.; Alvarez-Rivera, G.; Vendruscolo, R.G.; Voss, M.; da Silva, P.A.; Barin, J.S.; Jacob-Lopes, E.; Zepka, L.Q.; Wagner, R.

Use of high and ultra-high pressure based-processes for the effective recovery of bioactive compounds from Nannochloropsis oceanica microalgae

2021 Journal of Supercritical Fluids; vol: 167 ; Páginas: 1 - 18 Gallego, R.; Bueno, M.; Chourio, A.M.; Ibáñez, E.; Saldaña, M.D.A.; Herrero, M.

Impact of extreme obesity and diet-induced weight loss on the fecal metabolome and gut microbiota

2021 Mol. Nutr. Food Res. 65 (2021) 2000030; DOI: 10.1002/mnfr.202000030 A.M. Nogacka, C.G. de los Reyes-Gavilán, C. Martínez-Faedo, P. Ruas-Madiedo, A. Suarez, L. Mancabelli, M. Ventura, A. Cifuentes, C. León, M. Gueimonde, N. Salazar

Natural products in drug discovery: advances and opportunities

2021 Nature Reviews Drug Discovery 20 (2021) 200-216 DOI: 10.1038/s41573-020-00114-z A.G. Atanasov, C.T. Supuran, S.B. Zotchev, I.E. Orhan, M. Banach, J.M. Rollinger, D. Barreca, W. Weckwerth, R. Bauer, E.A. Bayer, M. Majeed, A. Bishayee, V. Bochkov, G.K. Bonn, N. Braidy, F. Bucar, A. Cifuentes, G. D’Onofrio, M. Bodkin, M. Diederich, A.T. Dinkova- Kostova, T. Efferth, K. El Bair, N. Arkells, T.P. Fan, B.L. Fiebich, M. Freissmuth, M.I. Georgiev, S. Gibbons, K.M. Godfrey, C.W. Gruber, J. Heer, L.A. Huber, E. Ibanez, A. Kijjoa, A.K. Kiss, A. Lu, F.A. Macias, M.J.S. Miller, A. Mocan, R. Müller, F. Nicoletti, G. Perry, V. Pittalà, L. Rastrelli, M. Ristow, G.L. Russo, A.S. Silva, D. Schuster, H. Sheridan, K. Skalicka- Woźniak, L. Skaltsounis, E. Sobarzo-Sánchez, D.S. Bredt, H. Stuppner, A. Sureda, N.T. Tzvetkov, R.A. Vacca, B.B. Aggarwal, M. Battino, F. Giampieri, M. Wink, J.L. Wolfender, J. Xiao, A.W.K. Yeung, G. Lizard, M.A. Popp, M. Heinrich, I. Berindan-Neagoe, M.Stadler, M. Daglia, R. Verpoorte

In-vitro neuroprotective potential of terpenes from industrial orange juice by-products

2021 Food & Funct. 12 (2021) 302-314, DOI: 10.1039/D0FO02809F J.D. Sánchez Martínez, M. Bueno, G. Alvarez-Rivera, J. Tudela, E. Ibañez, A. Cifuentes

Microwave-assisted extraction of phenolic compounds with antioxidant and anti-proliferative activities from supercritical CO2 pre-treated mango peel

2021 LWT - Food Sci. Tech. 137 (2021) 110414 DOI: 10.1016/j.lwt.2020.110414 A.P. Sánchez-Camargo, D. Ballesteros-Vivas, L.M. Buelvas-Puello, H.A. Martinez-Correa, F. Parada-Alfonso, A. Cifuentes, S.R.S. Ferreira, L.F. Gutiérrez

Phytochemical and functional characterization of phenolic compounds from cowpea (Vigna unguiculata) obtained by green extraction technologies

2021 Agronomy 11 (2021) 162. DOI: 10.3390/agronomy11010162 M.V. Avanza, G. Alvarez-Rivera, A. Cifuentes, J.A. Mendiola, E. Ibáñez

Phytosterol-rich compressed fluids extracts from Phormidium autumnale cyanobacteria with neuroprotective potential

2021 Algal Res. 55 (2021) 102264 DOI: 10.1016/j.algal.2021.102264 M. Bittencourt Fagundes, G. Alvarez-Rivera, J.A. Mendiola, M. Bueno, J.D. Sánchez-Martínez, R. Wagner, E. Jacob-Lopes, L. Queiroz Zepka, E. Ibañez, A. Cifuentes

Comprehensive phenolic and free amino acid analysis of rosemary infusions: influence on the antioxidant potential

2021 Antioxidants 10 (2021) 500. DOI: 10.3390/antiox10030500 (in press) J. Peixoto, G. Álvarez-Rivera, R.C. Alves, A. Costa, S. Machado, A. Cifuentes, E. Ibáñez. M.B. Oliveira,

Metabolite profiling of rosemary cell lines with antiproliferative potential against human HT-29 colon cancer cells

2021 Plant Food. Hum. Nutr. (in press) A. Urquiza-López, G. Álvarez-Rivera, D. Ballesteros-Vivas, A. Cifuentes, A.A. Del Villar-Martínez

Carotenogenesis of Staphylococcus aureus: new insights and impact on membrane biophysical properties

2021 Biochim. Biophys. Acta Mol. Cell Biol. Lipids (in press) G. Dirceu López, E. Suesca, G. Álvarez-Rivera, A.E. Rosato, E. Ibañez, A. Cifuentes, C. Leidy. C. Carazzone

Extraction and characterization of the polar lipid fraction of blackberry and passion fruit seeds oils using supercritical fluid extraction