Logo del grupo Bioactive Gastronomy

  • Contact mail:
  • Group leader: Marta Miguel Castro
  • Group website:

Group members

Research Staff

  • Marta Miguel Castro

Predoctoral Staff

  • Miguel López Moreno
  • Eva Bruna García


The main objective of our research group is to obtain ingredients and functional foods to improve the health, well-being and quality of life of people, whose biological basis and mechanism of action are scientifically supported, as well as to investigate the sensory and culinary characteristics of them. This research is carried out from a multidisciplinary point of view. The chemical and biochemical characterization of different food ingredients is addressed to investigate the relationship between structure-activity, and their biological properties are evaluated both in vitro and in vivo using different experimental models. Their digestibility and bioavailability are also studied, as well as their benefits and risks for human health through intervention studies in humans.

To achieve the technological adaptation of these bioactive ingredients, our research group also collaborates with renowned chefs and gastronomy experts, which has allowed a better and faster transfer of our developments to society. To date, we have obtained new textures from egg white hydrolysate. This product is currently marketed under the registered trademark Eggnergy Pro ®, thanks to the licensed agreement reached with the Spanish company Granja Campomayor. More recently, we have developed a 100% vegetable meat analog, based on carob, through the spin off, iLike Food Innovation S.L. Leggie ® is the registered trademark of this “vegetable meat” that is already on sale online in two formats, so you can customize your recipes (, or in prepared dish format (

Highlighted recent publications

  • Morales D, Miguel M, Garcés-Rimón M. Pseudocereals: a novel source of biologically active peptides. Critical Reviews in Food Science and Nutrition (2021) 61(9):1537-1544
  • López-Moreno M, Garcés-Rimón M, Miguel M. Iglesias López MT. Adherence to mediterranean diet, alcohol consumption and emocional eater study in university students. Nutrients 2021, 13(9), 3174;
  • Naya-Català F, Wiggers GA, Piazzon MC, López-Martínez MI, Estensoro I, Saez E, Calduch-Giner JA, Requena T, Sitjà-Bobadilla A, Miguel M, Pérez-Sánchez J. Modulation of gilthead sea bream gut microbiota by egg white hydrolysate (EWH): Interactions between bacteria, bile salts and host lipid metabolism. Frontiers in Marine Science, 2022, November 2021,
  • Bruna E, Isabel B, Miguel M*. New Method for Obtaining a Bioactive Essence Extracted from Iberian Ham Fat Rich in MUFA and Antioxidants. Molecules, 2022, 27, 428. * corresponding author
  • López-Moreno M, Garcés-Rimón M, Miguel M. Antinutrients: Lectins, goitrogens, phytates and oxalates, friends or foe?. Journal of Functional Foods. Lopez-Moreno et al. J Funct Foods, 2022, 89, 104938

Proyectos de Investigación vigentes

  • Title: Hidrólisis de proteínas vegetales de alto valor biológico: obtención de péptidos antioxidantes y nuevas texturas culinarias para la elaboración de productos sin gluten
    Reference: AGL-2017-89213
    Funded by: MICIIN
    Duration: 01-2018 / 09-2022
    Principal Investigator: Marta Miguel
  • Title: Hidrolizado de clara de huevo y salud cardiovascular. Estudio del efecto antihipertensivo y de los mecanismos de acción en ratas DOCA-sal
    Reference: Programa I-COOP+2020. COOPA20453
    Funded by: CSIC
    Duration: 01-2021 / 12-2022
    Principal Investigator: Marta Miguel

Contratos I+D con empresas vigentes

  • Title: Desarrollo de productos sobre la base de nuevos hidrolizados de clara de huevo de larga duración (OVOEXPAND)
    Reference: SOL-00150228
    Funded by: Campomayor-CDTI
    Duration: 04-2022 / 10-2023
    Principal Investigator: Marta Miguel

Knowledge transfer

Spin-off creation

  • iLike Food Innovation S.L.
    EBT fundada el 12 de junio de 2020 por Marta Garcés y Marta Miguel, Co-fundadoras
    Marca “Leggie” registrada y concedida en España y Europa
    Sublicencia de producción y comercialización en España y Europa para MRM SAU (4/12/2020)
    Producto comercializado y puesto a la venta desde octubre de 2021 en canal online ( /

Patents and industrial secrets

  • Type: Patent
    Inventors: M. Miguel, R. López-Alonso Fandiño, I. Recio. M Ramos González, y A. Aleixandre de Artiñano
    Title: Péptidos bioactivos derivados de proteínas de la clara de huevo mediante hidrólisis enzimática
    Funded by: Consejo Superior de Investigaciones Científicas.
    Country: Spain/International
    Aplication Number: 200301829 / PCT/Es2004/070059
    Aplication Date: 31/07/2003 – 23/07/2004
    Publication Nº: 2 253 036 / WO 2005/012355 A1
    Publication Date: 16/05/2006 – 10/02/2005
    Registral Situation: Concedida y en vigor
    Date of publication of concession: 16/07/2007
    Enterpise operating it: Bioactors, Brussels (Belgium) (since 11/03/2005)
  • Type: Patent
    Inventors: M Miguel, M Garcés, R López, M Sandoval
    Title: Composiciones alimentarias saludables que presentan texturas de gel o espuma y que comprenden ovoproductos hidrolizados
    Funded by: Consejo Superior de Investigaciones Científicas
    Country: Spain
    Aplication Number: P201331886
    Publication Date: 20 de diciembre de 2013
    Registral Situation: Concedida y en vigor
    Publication Date: 22/01/2016
    Enterprise operating it: ALCORP (07/07/2014)
    International enlargement: Protected in 145 countries, 10/12/2014
    Argentina: 20140104582
    USA: 14/566,363
    México: MX/A/2014/015135
    Japan: 2014-250005
    Enterpise operating it: ALCORP (since 07/07/2014) y Granja Campomayor (since 05/01/2018; sublicense to market in Spain and Europe)
  • Type: Know-how
    Authors: Miguel M, Jimenez E, Sandoval M, Conesa J, Gálvez M
    Titles: Hidrólisis de proteínas vegetales para la obtención de nuevas actividades biológicas, nuevas texturas y sus aplicaciones culinarias
    Funded by: Consejo Superior de Investigaciones Científicas-Mario Sandoval-Ecolife food
    Certificate of deposit requirement at the request of Consejo Superior de Investigaciones científicas (CSIC). Nº: 4018. Notary: Pedro-Antonio Mateos Salgado
    Aplicatioin place and date: Madrid, 21/07/2017
    Enterprise operating it: Ecolife Foods
  • Type: Patent
    Inventors: Miguel M, Bruna E, Redondo BI, Gómez J, Gómez Sánchez J
    Title: Extracto procedente de la grasa de cerdo, método de obtención, composición alimenticia que lo comprende y usos del mismo
    Funded by: Cárnicas Joselito S.L.
    Country: Spain
    Aplication Number: P2021130236
    Aplication Date: 17/03/2021
    Enterprise operating it: Cárnicas Joselito S.L.