- Contact mail: marta.miguel@csic.es
- Group leader: Marta Miguel Castro
- Group website: https://ilike.org.es/
Group members
Research Staff
- Marta Miguel Castro
Predoctoral Staff
- Miguel López Moreno
- Eva Bruna García
Summary
The main objective of our research group is to obtain ingredients and functional foods to improve the health, well-being and quality of life of people, whose biological basis and mechanism of action are scientifically supported, as well as to investigate the sensory and culinary characteristics of them. This research is carried out from a multidisciplinary point of view. The chemical and biochemical characterization of different food ingredients is addressed to investigate the relationship between structure-activity, and their biological properties are evaluated both in vitro and in vivo using different experimental models. Their digestibility and bioavailability are also studied, as well as their benefits and risks for human health through intervention studies in humans.
To achieve the technological adaptation of these bioactive ingredients, our research group also collaborates with renowned chefs and gastronomy experts, which has allowed a better and faster transfer of our developments to society. To date, we have obtained new textures from egg white hydrolysate. This product is currently marketed under the registered trademark Eggnergy Pro ®, thanks to the licensed agreement reached with the Spanish company Granja Campomayor. More recently, we have developed a 100% vegetable meat analog, based on carob, through the spin off, iLike Food Innovation S.L. Leggie ® is the registered trademark of this “vegetable meat” that is already on sale online in two formats, so you can customize your recipes (leggie@mrm.es), or in prepared dish format (https://www.tappers.es/at-home/leggie/).
Highlighted recent publications
- Morales D, Miguel M, Garcés-Rimón M. Pseudocereals: a novel source of biologically active peptides. Critical Reviews in Food Science and Nutrition (2021) 61(9):1537-1544
- López-Moreno M, Garcés-Rimón M, Miguel M. Iglesias López MT. Adherence to mediterranean diet, alcohol consumption and emocional eater study in university students. Nutrients 2021, 13(9), 3174; https://doi.org/10.3390/nu13093174
- Naya-Català F, Wiggers GA, Piazzon MC, López-Martínez MI, Estensoro I, Saez E, Calduch-Giner JA, Requena T, Sitjà-Bobadilla A, Miguel M, Pérez-Sánchez J. Modulation of gilthead sea bream gut microbiota by egg white hydrolysate (EWH): Interactions between bacteria, bile salts and host lipid metabolism. Frontiers in Marine Science, 2022, November 2021, https://doi.org/10.3389/fmars.2021.698484)
- Bruna E, Isabel B, Miguel M*. New Method for Obtaining a Bioactive Essence Extracted from Iberian Ham Fat Rich in MUFA and Antioxidants. Molecules, 2022, 27, 428. https://doi.org/10.3390/molecules27020428 * corresponding author
- López-Moreno M, Garcés-Rimón M, Miguel M. Antinutrients: Lectins, goitrogens, phytates and oxalates, friends or foe?. Journal of Functional Foods. Lopez-Moreno et al. J Funct Foods, 2022, 89, 104938
Proyectos de Investigación vigentes
- Title: Hidrólisis de proteínas vegetales de alto valor biológico: obtención de péptidos antioxidantes y nuevas texturas culinarias para la elaboración de productos sin gluten
Reference: AGL-2017-89213
Funded by: MICIIN
Duration: 01-2018 / 09-2022
Principal Investigator: Marta Miguel - Title: Hidrolizado de clara de huevo y salud cardiovascular. Estudio del efecto antihipertensivo y de los mecanismos de acción en ratas DOCA-sal
Reference: Programa I-COOP+2020. COOPA20453
Funded by: CSIC
Duration: 01-2021 / 12-2022
Principal Investigator: Marta Miguel
Contratos I+D con empresas vigentes
- Title: Desarrollo de productos sobre la base de nuevos hidrolizados de clara de huevo de larga duración (OVOEXPAND)
Reference: SOL-00150228
Funded by: Campomayor-CDTI
Duration: 04-2022 / 10-2023
Principal Investigator: Marta Miguel
Knowledge transfer
Spin-off creation
- iLike Food Innovation S.L.
EBT fundada el 12 de junio de 2020 por Marta Garcés y Marta Miguel, Co-fundadoras
Marca “Leggie” registrada y concedida en España y Europa
Sublicencia de producción y comercialización en España y Europa para MRM SAU (4/12/2020)
Producto comercializado y puesto a la venta desde octubre de 2021 en canal online (leggie@mrm.es / https://www.tappers.es/a-domicilio/leggie/)
Patents and industrial secrets
- Type: Patent
Inventors: M. Miguel, R. López-Alonso Fandiño, I. Recio. M Ramos González, y A. Aleixandre de Artiñano
Title: Péptidos bioactivos derivados de proteínas de la clara de huevo mediante hidrólisis enzimática
Funded by: Consejo Superior de Investigaciones Científicas.
Country: Spain/International
Aplication Number: 200301829 / PCT/Es2004/070059
Aplication Date: 31/07/2003 – 23/07/2004
Publication Nº: 2 253 036 / WO 2005/012355 A1
Publication Date: 16/05/2006 – 10/02/2005
Registral Situation: Concedida y en vigor
Date of publication of concession: 16/07/2007
Enterpise operating it: Bioactors, Brussels (Belgium) (since 11/03/2005) - Type: Patent
Inventors: M Miguel, M Garcés, R López, M Sandoval
Title: Composiciones alimentarias saludables que presentan texturas de gel o espuma y que comprenden ovoproductos hidrolizados
Funded by: Consejo Superior de Investigaciones Científicas
Country: Spain
Aplication Number: P201331886
Publication Date: 20 de diciembre de 2013
Registral Situation: Concedida y en vigor
Publication Date: 22/01/2016
Enterprise operating it: ALCORP (07/07/2014)
International enlargement: Protected in 145 countries, 10/12/2014
PCT/ES2014/070902
Argentina: 20140104582
USA: 14/566,363
México: MX/A/2014/015135
Japan: 2014-250005
Enterpise operating it: ALCORP (since 07/07/2014) y Granja Campomayor (since 05/01/2018; sublicense to market in Spain and Europe) - Type: Know-how
Authors: Miguel M, Jimenez E, Sandoval M, Conesa J, Gálvez M
Titles: Hidrólisis de proteínas vegetales para la obtención de nuevas actividades biológicas, nuevas texturas y sus aplicaciones culinarias
Funded by: Consejo Superior de Investigaciones Científicas-Mario Sandoval-Ecolife food
Certificate of deposit requirement at the request of Consejo Superior de Investigaciones científicas (CSIC). Nº: 4018. Notary: Pedro-Antonio Mateos Salgado
Aplicatioin place and date: Madrid, 21/07/2017
Enterprise operating it: Ecolife Foods - Type: Patent
Inventors: Miguel M, Bruna E, Redondo BI, Gómez J, Gómez Sánchez J
Title: Extracto procedente de la grasa de cerdo, método de obtención, composición alimenticia que lo comprende y usos del mismo
Funded by: Cárnicas Joselito S.L.
Country: Spain
Aplication Number: P2021130236
Aplication Date: 17/03/2021
Enterprise operating it: Cárnicas Joselito S.L.