FOODOMICS GROUP

grupo foodomics

Group members

Research Staff

  • Alejandro Cifuentes Gallego
  • M. Elena Ibáñez Ezequiel
  • Miguel Herrero Calleja

Predoctoral Staff

  • Tanize dos Santos Acunha
  • Lidia Montero García
  • Andrea del Pilar Sánchez Camargo
  • Natalia Pleite Guzman

Postdoctoral Staff

  • Bienvenida Gilbert López

Technical Staff

  • Carlos A. Cuellar Martín
  • José Antonio Mendiola León

Research Summary

In the Foodomics Laboratory we use and develop massive analytical techniques (transcriptomics, proteomics and metabolomics) to carry out our research in food and nutrition aspects such as bioactivity, safety and food quality at a molecular level. Our research lines include also the development of processes involving sub and supercritical fluids in order to obtain bioactive compounds and also, the development of advanced analytical methods based in coupled techniques (LC-MS, LCxLC-MS/MS, CE-MS, GC-MS, etc).

The objective of our recent work has to parts: i) to develop sub and supercritical fluids processes to obtain bioactive compounds from natural sources (mainly algae, microalgae, plants and food industry by-products) and ii) to study by Foodomic approach their effects in prevention and evolution of one of the diseases with higher incidence in our society, colon cancer. For this we use colon cancer cell lines and animal models, which may have important consequences in the prevention of this disease through the diet

Highlighted publications

  • M. Herrero, C. Simó, V. García-Cañas, E. Ibáñez, A. Cifuentes  “Foodomics: MS-based strategies in modern Food Science and Nutrition” Mass Spec. Rev. 31 (2012) 49–69
  • C. Ibáñez, A. Valdés, V. García-Cañas, C. Simó, M. Celebier, L. Rocamora, A. Gómez, M. Herrero, M. Castro, A. Segura-Carretero, E. Ibáñez, J.A. Ferragut, A. Cifuentes “Global Foodomics Strategy to Investigate the Health Benefits of Dietary Constituents” J. Chromatogr. A 1248 (2012) 139-153
  • V. García-Cañas, C. Simó, M. Herrero, E. Ibáñez, A. Cifuentes “Present and Future Challenges in Food Analysis. Foodomics” Anal. Chem. 84 (2012) 10150–10159
  • A. Valdés, V. García-Cañas, C. Simó, C. Ibáñez, J.A. Ferragut, V. Micol, A. Cifuentes “Comprehensive Foodomics study on the mechanisms operating at various molecular levels in cancer cells in response to individual rosemary polyphenols” Anal. Chem. 86 (2014) 9807-9815
  • B. Gilbert-López, J.A. Mendiola, J. Fontecha, L.A.M. van den Broek, L. Sijtsma, A. Cifuentes, M. Herrero, E. Ibáñez “Green downstream processing of Isochrysis galbana: A step towards microalgal biorefinery.” Green Chem. 17 (2015) 4599-4609